AskDefine | Define myocarditis

Dictionary Definition

myocarditis n : inflammation of the myocardium (the muscular tissue of the heart) [syn: myocardial inflammation]

User Contributed Dictionary

English

Noun

  1. In the context of "pathology|cardiology": Inflamation of the myocardium.

Extensive Definition

In medicine (cardiology), myocarditis is inflammation of the myocardium, the muscular part of the heart. It is generally due to infection (viral or bacterial). It may present with chest pain, rapid signs of heart failure, or sudden death.

Signs and symptoms

The signs and symptoms associated with myocarditis are varied, and relate either to the actual inflammation of the myocardium, or the weakness of the heart muscle that is secondary to the inflammation. Signs and symptoms of myocarditis include:
Since myocarditis is often due to a viral illness, many patients give a history of symptoms consistent with a recent viral infection, including fever, diarrhea, joint pains, and easy fatigueability.
Myocarditis is often associated with pericarditis, and many patients present with signs and symptoms that suggest concurrent myocarditis and pericarditis.

Diagnosis

Myocardial inflammation can be suspected on the basis of electrocardiographic results (ECG), elevated CRP and/or ESR and increased IgM (serology) against viruses known to affect the myocardium. Markers of myocardial damage (troponin or creatine kinase cardiac isoenzymes) are elevated.
Bacterial myocarditis is rare in patients without immunodeficiency.

Epidemiology

The exact incidence of myocarditis is unknown. However, in series of routine autopsies, 1–9% of all patients had evidence of myocardial inflammation. In young adults, up to 20% of all cases of sudden death are due to myocarditis.
In South America, Chagas' disease (caused by Trypanosoma cruzi) is the main cause of myocarditis.

Therapy

Bacterial infections are treated with antibiotics, dependent on the nature of the pathogen and its sensitivity to antibiotics. As most viral infections cannot be treated with directed therapy, symptomatic treatment is the only form of therapy for those forms of myocarditis, e.g. NSAIDs for the inflammatory component and diuretics and/or inotropes for ventricular failure. ACE inhibitor therapy may aid in the healing process.

References

myocarditis in German: Myokarditis
myocarditis in Spanish: Miocarditis
myocarditis in French: Myocardite
myocarditis in Italian: Miocardite
myocarditis in Japanese: 心筋炎
myocarditis in Polish: Zapalenie mięśnia sercowego
myocarditis in Portuguese: Miocardite
myocarditis in Finnish: Sydänlihastulehdus
myocarditis in Swedish: Hjärtmuskelinflammation
myocarditis in Vietnamese: Viêm cơ tim
Privacy Policy, About Us, Terms and Conditions, Contact Us
Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2
Material from Wikipedia, Wiktionary, Dict
Valid HTML 4.01 Strict, Valid CSS Level 2.1